Detalhe da pesquisa
1.
FAN1 modifies Huntington's disease progression by stabilizing the expanded HTT CAG repeat.
Hum Mol Genet
; 28(4): 650-661, 2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30358836
2.
Human Huntington's disease pluripotent stem cell-derived microglia develop normally but are abnormally hyper-reactive and release elevated levels of reactive oxygen species.
J Neuroinflammation
; 18(1): 94, 2021 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33874957
3.
Expression of mutant exon 1 huntingtin fragments in human neural stem cells and neurons causes inclusion formation and mitochondrial dysfunction.
FASEB J
; 34(6): 8139-8154, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32329133
4.
PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death.
Mol Cell
; 33(5): 627-38, 2009 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-19285945
5.
The role of the mitochondrial NCX in the mechanism of neurodegeneration in Parkinson's disease.
Adv Exp Med Biol
; 961: 241-9, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23224884
6.
Mislocalization of Nucleocytoplasmic Transport Proteins in Human Huntington's Disease PSC-Derived Striatal Neurons.
Front Cell Neurosci
; 15: 742763, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34658796
7.
An alternatively spliced form of glycogen synthase kinase-3beta is targeted to growing neurites and growth cones.
Mol Cell Neurosci
; 42(3): 184-94, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19607922
8.
What have PINK1 and HtrA2 genes told us about the role of mitochondria in Parkinson's disease?
Ann N Y Acad Sci
; 1147: 30-6, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19076428
9.
PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons.
PLoS One
; 3(6): e2455, 2008 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-18560593
10.
Glycogen synthase kinase-3beta phosphorylation of MAP1B at Ser1260 and Thr1265 is spatially restricted to growing axons.
J Cell Sci
; 118(Pt 5): 993-1005, 2005 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15731007